Doctors who carried out a stem cell transplant on an HIV-infected man with leukaemia in 2007 say they now believe the man to have been cured of HIV infection as a result of the treatment, which introduced stem cells which happened to be resistant to HIV infection.
The man received bone marrow from a donor who had natural resistance to HIV infection; this was due to a genetic profile which led to the CCR5 co-receptor being absent from his cells. The most common variety of HIV uses CCR5 as its ‘docking station’, attaching to it in order to enter and infect CD4 cells, and people with this mutation are almost completely protected against infection.
The case was first reported at the 2008 Conference on Retroviruses and Opportunistic Infections in Boston, and Berlin doctors subsequently published a detailed case history in the New England Journal of Medicine in February 2009.
They have now published a follow-up report in the journal Blood, arguing that based on the results of extensive tests, “It is reasonable to conclude that cure of HIV infection has been achieved in this patient.”
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An amazing anecdotal result that would be very costly to replicate in any numbers! But as far as the advancement of the understanding of HIV, this is phenomenal and could lead to many treatments!
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hows the weather? colder than a witch's titty ;)
ReplyDeleteBaww Wit da Baw dang it dang Humbug?? ;) Happy new Year
ReplyDeleteDamn is this shitty shitty bang bang Decade ever gonna fucking end. Are we there yet? are we there yet ? are we there yet ?
ReplyDeleteHappy New Year
so...how was your holiday.....?
ReplyDelete:P